Hepatocyte Embryonic Ectoderm Development (Eed) Deficiency Causes Liver Injury, Fibrosis and Impacts Liver Regeneration
Yousra Ajouaou, James Griffin, Sade Chaffatt, Charlene Chen, Balnur Ibrash, Martine McManus, Kirsten C. Sadler
This study shows that Eed deficiency in hepatocytes causes liver injury, fibrosis, and altered regeneration by disrupting H3K27me3 regulation of pro-regenerative genes.
bioRxiv · Jul 2, 2026 · PreprintPathology