Author

Jerren Ho

Aaron Diamond AIDS Research Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

David D. HoiD· 3 shared Qian WangiD· 3 shared Ian A. MellisiD· 2 shared Lawrence S. ShapiroiD· 2 shared Madeline Wu· 2 shared Yicheng GuoiD· 2 shared Anthony D. BoweniD· 1 shared Aubree GordoniD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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3 shared papersMicrobiology

David D. HoORCID

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Author profile →

3 papers

Recent·Most cited

Optimizing a Human Monoclonal Antibody for Better Neutralization of SARS-CoV-2

Qian Wang, Yicheng Guo, Ryan G. Casner, Jian Yu, Manoj S. Nair, Jerren Ho, Eswar R. Reddem, Ian A. Mellis, Madeline Wu, Chih-Chen Tzang, Hsiang Hong, Yaoxing Huang, Lawrence S. Shapiro, Lihong Liu, David D. Ho

This study optimizes a human monoclonal antibody to enhance its neutralization of SARS-CoV-2 variants, including subvariants XEC and LP.8.1, through structural analysis and engineering.

Nature Communications · Jul 4, 2025Peer-reviewedMicrobiology

Recurrent SARS-CoV-2 spike mutations confer growth advantages to select JN.1 sublineages

Qian Wang, Ian A. Mellis, Jerren Ho, Anthony D. Bowen, Theresa Kowalski-Dobson, Riccardo Valdez, Phinikoula S. Katsamba, Madeline Wu, Caitlin Lee, Lawrence S. Shapiro, Aubree Gordon, Yicheng Guo, David D. Ho, Lihong Liu

This study examines how recurrent spike mutations in SARS-CoV-2 JN.1 sublineages affect immune evasion, ACE2 affinity, and infectivity, identifying growth advantages in specific sublineages.

Emerging Microbes & Infections · Sep 11, 2024Peer-reviewedMicrobiology

Pemivibart is less active against recent SARS-CoV-2 JN.1 sublineages

Qian Wang, Yicheng Guo, Jerren Ho, David D. Ho

This study evaluates pemivibart's neutralizing activity against recent SARS-CoV-2 JN.1 sublineages and finds it has substantially reduced potency against KP.3.1.1.

bioRxiv · Aug 12, 2024 · PreprintImmunology