Author

Jia-Ming Chang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:benchmark study· 1 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:multiple species· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Aaron E. Darling· 1 shared Alexander Poliakov· 1 shared Benedict PateniD· 1 shared Bo-Hung Chen· 1 shared Brian Raney· 1 shared Carsten Kemena· 1 shared Cedric Notredame· 1 shared Cheng-Wen Wu· 1 shared

Activity by Year

2014-2018 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBioinformatics

Aaron E. Darling

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Targeting BMI1 and MCL1 for Lung Adenocarcinoma Treatment

Erh-Hsuan Lin, Chiung-Fang Hsu, Yi-Hua Jan, Tsung-Hsien Lin, Hsiang-Yi Chang, Chun-Ming Cheng, Hui-Jan Hsu, Wei-Wei Chen, Bo-Hung Chen, Hsing-Fang Tsai, Jung-Jung Li, Chi-Ying Huang, Shih-Hsien Chuang, Jia-Ming Chang, Michael Hsiao, Cheng-Wen Wu

This study identifies BMI1 and MCL1 as key drivers of lung adenocarcinoma progression and demonstrates that targeting these proteins with a novel small-molecule inhibitor suppresses tumor growth in preclinical models.

bioRxiv · Oct 22, 2018 · PreprintCancer Biology

Alignathon: A competitive assessment of whole genome alignment methods.

Dent Earl, Ngan K Nguyen, Glenn Hickey, Robert S. Harris, Stephen Fitzgerald, Kathryn Beal, Igor Seledtsov, Vladimir Molodtsov, Brian Raney, Hiram Clawson, Jaebum Kim, Carsten Kemena, Jia-Ming Chang, Ionas Erb, Alexander Poliakov, , Benedict Paten

The paper organizes a competitive evaluation of whole genome alignment methods using simulated and real datasets, finding significant accuracy differences between tools and performance variations across evolutionary distances.

Genome Research · Oct 1, 2014Peer-reviewedBioinformatics