Michael Hsiao

This study develops NCLscan-hybrid to detect intragenic trans-spliced RNAs in cancer cells and validates their role in tumor growth and apoptosis.

This study shows TAOK3 overexpression correlates with poor prognosis and paclitaxel resistance in lung adenocarcinoma, suggesting it as a therapeutic target.

This study identifies BMI1 and MCL1 as key drivers of lung adenocarcinoma progression and demonstrates that targeting these proteins with a novel small-molecule inhibitor suppresses tumor growth in preclinical models.

This study identifies AK4 as a driver of lung cancer metastasis by modulating oxidative stress and stabilizing HIF-1α, with potential therapeutic targeting of the AK4-HIF-1 axis.