Proteomic composition and mutual assembly of the C2a projection in vertebrate motile cilia
Qian Lyu, Qingchao Li, Jingrui Li, Jiajun Luo, Chunyu Liu, Shanshan Nai, Hongbin Liu, Xueliang Zhu, Ting Song, Min Liu, Huijie Zhao
The paper identifies the proteomic composition and functional interdependence of the vertebrate C2a projection, showing that loss of any of three proteins causes ciliary dysfunction and primary ciliary dyskinesia in mice.
bioRxiv · Jun 1, 2026Cell Biology