Endothelial MRG15 Is a Mechanosensitive Suppressor of Atherosclerosis
Yongbo Li, Xiaoke Lin, Jinghua Ma, Qingjun Jiang, Jiayi Lin, Lefeng Qu, Qiurong Ding, Xiangxiang Wei, Xiuling Zhi, Panpan Zhang, John Y.-J. Shyy, Elena Osto, Yuxiang Dai, Jieyu Guo, Dan Meng
This study identifies MRG15 as a mechanosensitive suppressor of atherosclerosis by showing its role in regulating endothelial inflammation and adhesion pathways under disturbed flow.
bioRxiv · Jan 30, 2026 · PreprintMolecular Biology