Hedgehog Pathway Activity Downstream of Smoothened is regulated specifically by Basal Ciliary PKA
Hongyu Zhang, Shujing Chen, Zhuoya Huang, Jin Ben, Yanling Wei, G. Chen, Changxin Wu, Haibo Xie, Philip William Ingham, Zhonghua Zhao
This study investigates how PKA activity in primary cilia regulates the Hedgehog pathway, showing that ciliary PKA specifically modulates the pathway even when cilia are disrupted.
Cellular & Molecular Biology Letters · Apr 9, 2026Peer-reviewedCell Biology