Author

Jixin Cui

Amgen (United States)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

Chi-Ming LiiD· 3 shared Junedh AmruteiD· 3 shared Kory J. LavineiD· 3 shared Tracy YamawakiiD· 3 shared Andrea L. BredemeyeriD· 2 shared Brandon L. Ason· 2 shared Chang Jie Mick LeeiD· 2 shared Daniel KreiseliD· 2 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersGenomics

Chi-Ming LiORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Targeting Modulated Vascular Smooth Muscle Cells in Atherosclerosis via FAP-Directed Immunotherapy

Junedh Amrute, In‐Hyuk Jung, Tracy Yamawaki, Wen-Ling Lin, Andrea L. Bredemeyer, Johanna Diekmann, Sikander Hayat, Xianglong Zhang, Devin L. Wakefield, Xin Luo, Sidrah Maryam, Gyu Seong Heo, Steven Hoseong Yang, Chang Jie Mick Lee, Chen Wang, , Kory J. Lavine

Single-cell and spatial maps of human coronary arteries identify FAP as a marker of SMC-derived modulated cells; an anti-FAP BiTE reduced plaque burden in mouse models.

Science · Jan 29, 2026Peer-reviewedGenomics✦ In-depth digest

Targeting RUNX1 in Macrophages Facilitates Cardiac Recovery

Junedh Amrute, Ada Zhu, Yun-Ling Pai, Melissa Hector-Greene, Yuqian An, Kenji Rowell Kim, Maya U. Sheth, Arun Padmanabhan, Clara Youngna Lee, Tracy Yamawaki, Florian Sicklinger, Niklas Hartman, Andrea L. Bredemeyer, Chang Jie Mick Lee, Vee Xu, , Kory J. Lavine

This study identifies RUNX1 as a key regulator of cardiac recovery by reprogramming macrophages, showing that its inhibition promotes heart function recovery in a chronic heart failure model.

bioRxiv · Jul 25, 2025 · PreprintImmunology

Dissecting Regulatory Non-Coding Heart Disease GWAS Loci with High-Resolution 3D Chromatin Interactions Reveals Causal Genes with Pathophysiological Relevance to Heart Failure

Richard Gill, Daniel Lu, Ittai E. Eres, Jiamiao Lu, Jixin Cui, Zhongsheng Yu, Tracy Yamawaki, Hong Zhou, Baikang Pei, Junedh Amrute, Yen-Sin Ang, Songli Wang, Kory J. Lavine, Brandon L. Ason, Chi-Ming Li, Yi‐Hsiang Hsu

The paper identifies causal genes in heart disease GWAS loci by integrating Hi-C, chromatin accessibility, and transcriptomic data, revealing regulatory relationships in cardiac fibroblasts.

bioRxiv · Oct 8, 2024 · PreprintGenomics