Author

Vee Xu

Gladstone Institutes

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Genomics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:clustering· 1 Assay:CRISPR screen· 1

Frequent Co-Authors

Arun PadmanabhaniD· 2 shared Brandon L. Ason· 2 shared Chi-Ming LiiD· 2 shared Clara Youngna LeeiD· 2 shared J EngreitziD· 2 shared Junedh AmruteiD· 2 shared Maya U. ShethiD· 2 shared Michael AlexanianiD· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersGenomics

Arun PadmanabhanORCID

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Author profile →

3 papers

Recent·Most cited

A Compact Regulatory Logic Governs Fibroblast Cell State Plasticity in Fibrosis

Ada M. Zhu, Yeting Li, Haiwei Zhang, Brindha Rathinasabapathi, Bastien Cimarosti, Rangarajan D. Nadadur, Vee Xu, Yu Huang, Yuqian An, Kirsten Auclair, Alicja Mahr, Maya U. Sheth, Clara Youngna Lee, Chen Wang, Tracy Yamawaki, , Michael Alexanian

The paper identifies a compact regulatory logic governing fibroblast plasticity in fibrosis by analyzing enhancer repression and gene perturbations across multiple tissues.

bioRxiv · Oct 16, 2026 · PreprintGenomics

Targeting RUNX1 in Macrophages Facilitates Cardiac Recovery

Junedh Amrute, Ada Zhu, Yun-Ling Pai, Melissa Hector-Greene, Yuqian An, Kenji Rowell Kim, Maya U. Sheth, Arun Padmanabhan, Clara Youngna Lee, Tracy Yamawaki, Florian Sicklinger, Niklas Hartman, Andrea L. Bredemeyer, Chang Jie Mick Lee, Vee Xu, , Kory J. Lavine

This study identifies RUNX1 as a key regulator of cardiac recovery by reprogramming macrophages, showing that its inhibition promotes heart function recovery in a chronic heart failure model.

bioRxiv · Jul 25, 2025 · PreprintImmunology

A designed Zn2+ sensor domain transmits binding information to transmembrane histidine kinases

A. Katherine Hatstat, Rian C. Kormos, Vee Xu, Guoming Du, Lijun Liu, Shaoqing Zhang, William F. DeGrado

The paper demonstrates the feasibility of engineering a transmembrane histidine kinase with a de novo metal-binding sensor domain that transmits binding information.

Journal of the American Chemical Society · May 19, 2025Peer-reviewedBiochemistry