Author

John Adeleye

Broad Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Bryan J. SongiD· 2 shared Deeksha Misri· 2 shared Hasmik KeshishianiD· 2 shared Horia PribiagiD· 2 shared Joshua Z. LeviniD· 2 shared Kira A. Perzel MandelliD· 2 shared Morgan ShengiD· 2 shared Nolan D. HartleyiD· 2 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersNeuroscience

Bryan J. SongORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Elevated synaptic PKA activity and abnormal striatal dopamine signaling in Akap11 mutant mice, a genetic model of schizophrenia and bipolar disorder

Bryan J. Song, Yang Ge, Ally A. Nicolella, Min Jee Kwon, Bart Lodder, Kevin Bonanno, Antia Valle-Tojeiro, Nolan D. Hartley, Kira Perzel Mandell, John Adeleye, Deeksha Misri, Chuhan Geng, Sahana Natarajan, Inès Picard, Nate Shepard, , Morgan Sheng

This study investigates Akap11 mutant mice to explore the neurobiological effects of AKAP11 loss, finding increased PKA activity and transcriptomic changes linked to schizophrenia and bipolar disorder.

Nature Communications · Nov 28, 2025Peer-reviewedNeuroscience

Abnormal Lipid Metabolism and Altered Neuronal Support by Astrocytes Lacking Akap11, a Risk Gene for Schizophrenia and Bipolar Disorder

Xiao‐Man Liu, Horia Pribiag, Deeksha Misri, Kwanho Kim, Kira A. Perzel Mandell, Bryan J. Song, David R. Graykowski, Olivia Seidel, Nolan D. Hartley, Mateo Herrera, Haiyun Xu, Matthew Tegtmeyer, Yan-Ling Zhang, Lei Cui, Natalie M. Clark, , Morgan Sheng

This study identifies AKAP11's role in regulating lipid metabolism and neuronal support in astrocytes, linking its dysfunction to schizophrenia and bipolar disorder risk.

bioRxiv · Apr 25, 2025 · PreprintCell Biology