Author

John Choi

Brigham and Women's Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Assay:electronic health records· 1 Research Focus:host-pathogen & immune response· 1 Organism:non-human primate· 1

Frequent Co-Authors

Agrita DubeyiD· 1 shared Anand Chellappan ReghuvaraniD· 1 shared Ashwani Kumar· 1 shared Barbara FranchiniD· 1 shared Bijan PesaraniD· 1 shared Bony De KumariD· 1 shared Cijiang HeiD· 1 shared E. M. TanviriD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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1 shared paperNeuroscience

Agrita DubeyORCID

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3 papers

Recent·Most cited

Glioblastoma model mouse rescue from mortality by brain-targeted catalytically-enhanced angiotensin-converting enzyme 2 mutant-antibody fusion protein

Pete Heinzelman, George R Nageeb, John Choi, Justin Liu, Si Yeon Lee, Philip A Romero, Michael Lim

The paper shows that combining ACE2dm-s1 with a STING agonist improves survival in GBM model mice, unlike losartan alone, and suggests ACE2dm-s1 modulates the tumor microenvironment.

bioRxiv · Nov 4, 2026 · PreprintCancer Biology

Scalable hardware and software for high-density, multi-regional electrophysiology in non-human primates

Agrita Dubey, Qia Xu, Mohammad Farhan Khazali, John Choi, Katie Wingel, Jarl Haggerty, Jacob Stefanowicz, Bijan Pesaran

The paper introduces MIND and UnitAssay for scalable, high-density, multi-regional electrophysiology in non-human primates, enabling stable recordings and reliable single-unit identification.

bioRxiv · Oct 27, 2026 · PreprintNeuroscience

A T-cell Intrinsic Role for APOL1 Risk Alleles in Allograft Rejection

John F. Pell, E. M. Tanvir, Zhengliang Sun, Irene Chernova, Anand Chellappan Reghuvaran, Soichiro Nagata, Mateus Guerra, John Choi, Soltan Al Chaar, Hiroki Mizuno, Ke Dong, Xin Tian, Reika Ishibe, Barbara Franchin, Paolo Cravedi, , Madhav C. Menon

This study identifies a T-cell intrinsic mechanism by which APOL1 risk alleles contribute to kidney rejection through altered calcium signaling and T-cell activation.

American Journal of Transplantation · Aug 1, 2025Peer-reviewedImmunology