Transcription factors GAF and HSF act at distinct regulatory steps to modulate stress-induced gene activation
Fabiana M Duarte, Nicholas J Fuda, Dig B Mahat, Leighton J Core, Michael Guertin, John T Lis
This study investigates the distinct roles of transcription factors GAF and HSF in the heat shock response in Drosophila using PRO-seq, revealing their separate functions in Pol II pausing and release during gene activation.
bioRxiv · May 27, 2016Genomics