Author

John Wainwright

George Washington University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:rat· 1

Frequent Co-Authors

David MendelowitziD· 1 shared Joan B. Escobar· 1 shared John R. BetheaiD· 1 shared Matthew W. KayiD· 1 shared Olga DergachevaiD· 1 shared Vivek JainiD· 1 shared Vsevolod Y. PolotskyiD· 1 shared X Wang· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperPharmacology & Toxicology

David MendelowitzORCID

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1 paper

Recent·Most cited

Oxytocin treats respiratory depression and reduces mortality from fentanyl and the combination of xylazine-fentanyl

Joan B. Escobar, John Wainwright, X Wang, Olga Dergacheva, Matthew W. Kay, John R. Bethea, Vivek Jain, Vsevolod Y. Polotsky, David Mendelowitz

This study shows oxytocin improves survival and respiratory function in rats with opioid-induced respiratory depression caused by fentanyl or fentanyl-xylazine combinations, outperforming naloxone in some cases.

bioRxiv · Feb 24, 2026 · PreprintPharmacology & Toxicology