Author

Jonathan Royaert

KU Leuven

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Jelle Verbeeck· 2 shared Kim De KeersmaeckeriD· 2 shared Anaïs AstieriD· 1 shared Anaís Sánchez‐CastilloiD· 1 shared Annalisa OcchipintiiD· 1 shared Carine FromentiD· 1 shared Célia Plisson‐ChastangiD· 1 shared Claudio AngioneiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCancer Biology

Jelle Verbeeck

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Sertraline and Carfilzomib Synergize to Target T-cell Malignancies with Serine/Glycine synthesis activity via Cholesterol Dysregulation, Cellular Stress and Immune Modulation

Paulien Verstraete, Elien Heylen, Anaís Sánchez‐Castillo, João Fontela, Lies Matthys, Sofie Meykens, Óscar Herranz, Suraj Verma, Le Minh Thao Doan, Linde Van Aerschot, Jelle Verbeeck, Jonathan Royaert, Michiel Vandenbosch, Ruben Jacobs, Gabriella Dow, , Kim De Keersmaecker

This paper shows that sertraline and carfilzomib work together to kill T-cell cancers by disrupting metabolism and changing the immune environment.

bioRxiv · Aug 19, 2026 · PreprintCancer Biology

Translatome and translation dynamics analysis of a RiboCancer cell line panel reveals that leukemia-associated Rps15 mutations rewire translation through codon-specific tRNA accommodation defects.

Anaïs Astier, Marino Caruso, Stijn Vereecke, Paulo E. Santo, Coralie Capron, Carine Froment, Dana Rinaldi, David Cabrerizo Granados, Marine Leclercq, Jonathan Royaert, Jelle Verbeeck, Naomy Pasau, Laura Plassart, Daniele Pepe, Steven Verbruggen, , Kim De Keersmaecker

The paper analyzes translatome and translation dynamics in RiboCancer cell lines to show that Rps15 mutations disrupt tRNA accommodation, affecting translation efficiency and transcriptional regulation in CLL.

HemaSphere · Jun 1, 2026Peer-reviewedMolecular Biology