Rostral Pedunculopontine Nucleus Infusion of M4 Positive Allosteric Modulator VU0467154 Augments L-DOPA Effects in Hemiparkinsonian Rats
Nicole Chambers, Annique McLune, Michael Coyle, Ashley Centner, Jordan Sergio, Isabella Delpriore, Kathryn Lanza, Craig W. Lindsley, Peter Jeffrey Conn, Christopher Bishop
This study investigates the effect of M4 receptor activation in the pedunculopontine nucleus on L-DOPA-induced dyskinesia and motor function in hemiparkinsonian rats.
bioRxiv · Apr 16, 2024 · PreprintNeuroscience