Author

Joseph Vavra

University of Minnesota

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 1 Research Focus:clustering· 1 Approach:contrastive learning· 1 Approach:deep learning· 1 Approach:experimental assay· 1

Frequent Co-Authors

Cailong HuaiD· 2 shared James M. ErvastiiD· 2 shared Joseph M. MurettaiD· 2 shared Murti V. SalapakaiD· 2 shared Jacob Powers· 1 shared Rebecca A Walsh· 1 shared Vinitendra Singh· 1 shared Yiyuan ZhangiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

8 top collaborators · 25 mutual co-author links

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2 shared papersBiophysics

Cailong HuaORCID

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2 papers

Recent·Most cited

Resolving Heterogeneous Mechanical Domains via Physics-Aware Deep Clustering of Single-Molecule Force Spectroscopy Data

Cailong Hua, Yiyuan Zhang, Vinitendra Singh, Rebecca A Walsh, Joseph Vavra, Joseph M. Muretta, James M. Ervasti, Murti V. Salapaka

This paper introduces a physics-aware deep clustering method to identify heterogeneous folding domains in single-molecule force spectroscopy data, revealing distinct mechanical properties in natural proteins.

bioRxiv · Sep 1, 2026 · PreprintBiophysics

Two operational modes of atomic force microscopy reveal similar mechanical properties for homologous regions of dystrophin and utrophin

Cailong Hua, Joseph Vavra, Jacob Powers, Joseph M. Muretta, James M. Ervasti, Murti V. Salapaka

This study compares the mechanical properties of dystrophin and utrophin fragments using AFM, finding bacterial utrophin is less stiff than insect utrophin, while dystrophin is intermediate.

Proceedings of the National Academy of Sciences · Jan 14, 2026Peer-reviewedBiophysics