Impact of O-GlcNAcylation elevation on mitophagy and glia in the dentate gyrus
Joshua Kramer, Sarah Yu Fu, Xiaosen Ouyang, Eric Rohwer, John C. Chatham, Martin Elliot Young, Victor M. Darley-Usmar, Jianhua Zhang
This study shows that elevated O-GlcNAcylation reduces mitophagy in astrocytes and alters glia homeostasis in the dentate gyrus.
Journal of Neurochemistry · Aug 1, 2025Peer-reviewedNeuroscience