The Role of Glycosphingolipids in Autoimmune Manifestations and Myeloma in Gaucher Disease
Elena Pavlova, Joy Archer, Maria J. Ferraz, Johannes M. F. G. Aerts, Timothy Martin Cox
This study investigates the role of glycosphingolipids in autoimmune manifestations and myeloma in Gaucher disease using a mouse model and finds that CD1 molecules regulate inflammation and tumour formation but not monoclonal immunoglobulin production.
bioRxiv · Jul 28, 2025 · PreprintPathology