Brain-Resident CD8+ T Cells Regulate Neuronal Activity and Behavior via Interferon-Gamma
Kyungsoo Park, Juneil Jang, Shin Jeon, Sunsook Hwang, Kyuhyun Choi, timothy cox, Shin Foong Ngiow, julia flores, Camille F. Harrison, Shuaitong Liu, F. Chris Bennett, Michael A. Silverman, E. John Wherry, Christoph A. Thaiss, Marc Vincent Fuccillo, Yeong Shin Yim
This study identifies brain-resident CD8+ T cells that regulate neuronal activity and behavior through interferon-gamma secretion, showing their role in maintaining brain homeostasis.
bioRxiv · Oct 10, 2026 · PreprintImmunology