Yeong Shin Yim

This study identifies conserved functional features of brain-associated CD8+ T cells in mice and marmosets and shows how brain signals regulate their effector programs.

This study identifies brain-resident CD8+ T cells that regulate neuronal activity and behavior through interferon-gamma secretion, showing their role in maintaining brain homeostasis.

This study shows that delivering FOXG1 to neurons via AAV vectors improves oligodendrocyte maturation, myelination, and hippocampal structure in mouse models of FOXG1 syndrome.

This study identifies distinct brain-resident immune cell populations with unique transcriptional profiles, showing age-related changes and altered interactions in Alzheimer's disease.