The atypical cadherin CELSR2 regulates distinct epithelial-mesenchymal states and oxidative phosphorylation in triple-negative breast cancer
Julia Koren, Nour-Islem Yanis Saidani, Abdessamad El Kaoutari, Avais M. Daulat, Pascal Finetti, Emmanuelle Josselin, Stéphane Audebert, Luc Camoin, Roxanne A Gauthier, Rémy Castellano, Arthur Géraud Cremieux, Fabienne Lamballe, François Bertucci, Flavio Maina, Jean‐Paul Borg, Alexandra Walton
This study identifies CELSR2 as a regulator of epithelial-mesenchymal plasticity and oxidative phosphorylation in triple-negative breast cancer, showing its role in shaping tumor heterogeneity.
bioRxiv · Sep 17, 2026 · PreprintCancer Biology