Glutathione Protects Hematopoietic Stem Cells from Proteotoxic Stress
Animesh Paul, Harrison J. Tom, Salma Merchant, Julia Phan, Andrew S. Lemoff, Thomas P. Mathews, Courtney M. Karner, Gerta Hoxaj, Zhiyu Zhao, Sean J. Morrison
This study shows that glutathione is essential for proteostasis in hematopoietic stem cells but not for ferroptosis prevention.
bioRxiv · Oct 6, 2026 · PreprintCell Biology