Nonlinear dynamic genetic regulation identifies peripheral drivers of neurodegenerative disease progression
Junfeng Luo, Hao Wu, Wenxuan Du, the Frontotemporal Lobar Degeneration Neuroimaging Initiative, Ganqiang Liu
This study identifies peripheral genetic drivers of neurodegenerative disease progression using a novel two-stage framework linking genetic variants to longitudinal molecular traits and disease phenotypes.
medRxiv · Jan 30, 2026 · PreprintGenetic & Genomic Medicine