Glioblastoma Hijacks Astrocyte Ribosomes to Feul Malignancy through Translatome Reprogramming
Xujia Wu, Chen Zheng, Lanjie Chen, Junju Chen, Yuchao Zhang, Long Cheng, Yushan Peng, Xuechao Zeng, Mingpu Gao, Feng Luo, Yanxing Lai, Jiying Cheng, Yixin Gao, Jian Zhong, Xuesong Yang, , Nu Zhang
This study shows glioblastoma hijacks astrocyte ribosomes via tunneling nanotubes, reprograms the tumor translatome to promote malignancy, and identifies INTS12 as a therapeutic target.
bioRxiv · Oct 29, 2026 · PreprintCancer Biology