Author

K. Backus

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

A. R. Julio· 1 shared A. Turmon· 1 shared C. Truong· 1 shared E. Dominguez· 1 shared F. Shikwana· 1 shared J. Cao· 1 shared L. Boatner· 1 shared L. Cui· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBiochemistry

A. R. Julio

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2 papers

Recent·Most cited

Pervasive aggregation and depletion of host and viral proteins in response to cysteine-reactive electrophilic compounds

A. R. Julio, F. Shikwana, C. Truong, N. R. Burton, E. Dominguez, A. Turmon, J. Cao, K. Backus

The paper identifies a cysteine-reactive small molecule degrader of SARS-CoV-2 nsp14, showing it causes protein aggregation, depletion, and stress granule formation in cells.

bioRxiv · Oct 30, 2023 · PreprintBiochemistry

Defining the Cell Surface Cysteinome using Two-step Enrichment Proteomics

T. Yan, L. Boatner, L. Cui, P. Tontonoz, K. Backus

The paper introduces a two-stage enrichment method called Cys-Surf to profile the cell surface cysteinome, identifying 821 ligandable cysteines and redox-sensitive residues with functional implications.

bioRxiv · Oct 17, 2023Biochemistry