Author

K. Barrack

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 5

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:metagenomics· 3 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

G. O'Toole· 5 shared R. Valls· 4 shared T. H. Hampton· 3 shared C. E. Price· 2 shared J. C. Madan· 2 shared J. Madan· 2 shared M. Coker· 2 shared A. Ramsey· 1 shared

Activity by Year

2021-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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5 shared papersMicrobiology

G. O'Toole

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Author profile →

5 papers

Recent·Most cited

An In Vitro Medium for Modeling Gut Dysbiosis Associated with Cystic Fibrosis

K. Barrack, T. H. Hampton, R. Valls, S. Surve, T. Gardner, J. Sanville, J. Madan, G. O'Toole

This paper develops a novel in vitro culture medium, CF-MiPro, that mimics the CF gut environment and alters non-CF microbiomes to resemble CF-like profiles.

bioRxiv · Aug 1, 2023Microbiology

Predicting Clinical Outcomes in Infants With Cystic Fibrosis From Stool Microbiota using Random Forest Algorithms

R. Valls, T. H. Hampton, C. E. Price, K. Barrack, G. O'Toole, M. Coker, J. C. Madan

This paper uses random forest algorithms to predict clinical outcomes in children with cystic fibrosis based on stool microbiota composition.

bioRxiv · Aug 6, 2022 · PreprintMicrobiology

Development of the Intestinal Microbiome in Cystic Fibrosis in Early Life

C. E. Price, T. H. Hampton, R. Valls, K. Barrack, G. O'Toole, J. C. Madan, M. Coker

This study tracks the development of the gut microbiome in children with cystic fibrosis from birth to age 4, finding persistent dysbiosis and early signs of inflammatory bowel disease-associated microbiota.

bioRxiv · May 27, 2022Microbiology

Intestinal Bacteroides Modulates Systemic Inflammation and the Microbial Ecology in a Mouse Model of CF: Evidence for Propionate and other Short Chain Fatty Acids Reducing Systemic Inflammatory Cytokines

C. Price, R. Valls, A. Ramsey, N. Loeven, J. Jones, K. Barrack, J. Schwartzman, D. Royce, R. A. Cramer, J. Madan, B. Ross, J. B. Bliska, G. O'Toole

This study shows that Bacteroides in CF patients reduces systemic inflammation via propionate and alters microbial ecology in a mouse model of CF.

bioRxiv · Jan 5, 2022 · PreprintMicrobiology

The Diguanylate Cyclase YfiN of Pseudomonas aeruginosa Regulates Biofilm Maintenance in Response to Peroxide

S. Katharios-Lanwermeyer, S. Koval, K. Barrack, G. O'Toole

This study shows that YfiN, a diguanylate cyclase in P. aeruginosa, regulates biofilm maintenance by controlling c-di-GMP levels, motility, and viability under peroxide stress.

bioRxiv · Jul 29, 2021Microbiology