The bacterial leader peptide peTrpL has a conserved function in antibiotic-dependent posttranscriptional regulation of ribosomal genes
H. Melior, S. Maass, M. Stoetzel, S. Li, K. U. Foerstner, R. Schuetz, S. Azarderakhsh, A. Shevkoplias, S. Barth-Weber, A. R. Varadarajan, K. Baumgardt, Z. Chervontseva, J. Ziebuhr, C. H. Ahrens, D. Becher, E. Evguenieva-Hackenberg
The paper identifies peTrpL as a conserved bacterial leader peptide that, along with rnTrpL, mediates tetracycline-dependent destabilization of ribosomal protein mRNAs.
bioRxiv · Sep 26, 2019Microbiology