Effective use of genetically-encoded optical biosensors for profiling signalling signatures in iPSC-CMs derived from idiopathic dilated cardiomyopathy patients
K. Bourque, I. Derish, C. Hawey, J. Jones-Tabah, K. Khan, K. Alim, A. Jiang, H. Sadighian, J. Zwaig, N. Gendron, R. Cecere, N. Giannetti, T. Hebert
The paper uses patient-derived iPSC-CMs and optical biosensors to profile signaling changes in idiopathic dilated cardiomyopathy, aiming to uncover personalized disease mechanisms and therapeutic targets.
bioRxiv · Sep 6, 2022 · PreprintBiochemistry