T. Hebert

The Orphan G Protein-Coupled Receptor GPR52 is a Novel Regulator of Breast Cancer Multicellular Organization

This study shows that loss of GPR52 in breast cancer cells increases cell clustering, EMT features, and tumor burden in zebrafish, suggesting GPR52 as a potential therapeutic target.

Effective use of genetically-encoded optical biosensors for profiling signalling signatures in iPSC-CMs derived from idiopathic dilated cardiomyopathy patients

The paper uses patient-derived iPSC-CMs and optical biosensors to profile signaling changes in idiopathic dilated cardiomyopathy, aiming to uncover personalized disease mechanisms and therapeutic targets.

Comparing the signaling and transcriptome profiling landscapes of human iPSC-derived and primary rat neonatal cardiomyocytes

This study compares signaling and transcriptome profiles of human iPSC-derived and primary rat cardiomyocytes to assess their suitability as models for cardiac research.

Addition of a carboxy terminal tail to the normally tailless gonadotropin-releasing hormone receptor impairs fertility in female mice

This study shows that adding a C-terminal tail to the tailless murine GnRHR impairs fertility by reducing FSH production and ovarian follicle development.

A comparison of eDNA to camera trapping for assessment of terrestrial mammal diversity

This study compares eDNA analysis of soil samples with camera trapping for terrestrial mammal diversity assessment, finding eDNA detects all camera-confirmed species and additional small mammals.

Return of an apex predator to a suburban preserve triggers a rapid trophic cascade

The paper shows that the return of pumas to a suburban area rapidly triggered a trophic cascade, affecting prey and competitor species through multiple methods.