K. D. Hunter

Extracellular prostaglandins E1 and E2 and inflammatory cytokines are regulated by the senescence program in potentially premalignant oral keratinocytes

This study shows that senescence in premalignant oral keratinocytes increases extracellular prostaglandins E1 and E2 and inflammatory cytokines, which may promote progression to oral SCC through paracrine signaling.

The role of icIL-1RA type 1 in oral keratinocyte senescence and the development of the senescence associated secretory phenotype

This study shows that loss of icIL-1RA1 promotes SASP in oral keratinocytes, contributing to a pro-inflammatory environment that may facilitate cancer development.