Cell BiologybioRxiv
Extracellular prostaglandins E1 and E2 and inflammatory cytokines are regulated by the senescence program in potentially premalignant oral keratinocytes
L. P. Karen-Ng, U. S. Ahmad, L. Gomes…·E. Parkinson
This study shows that senescence in premalignant oral keratinocytes increases extracellular prostaglandins E1 and E2 and inflammatory cytokines, which may promote progression to oral SCC through paracrine signaling.
DOI 10.3390/cancers14112636