Human immunodeficiency virus integration complexes are active following ordered addition of wild type integrase, viral DNA, and LEDGF/p75
A. J. Rabe, J. A. Russo, R. C. Larue, K. E. Yoder
The paper tests the order of assembly of HIV-1 integrase, LEDGF/p75, and viral DNA in integration complexes and finds that adding LEDGF/p75 last maximizes integration efficiency.
bioRxiv · Sep 19, 2022 · PreprintBiochemistry