Massively parallel single molecule tracking of sequence-dependent DNA mismatch repair in vivo
T. Kayikcioglu, J. S. Zarb, S. Mohapatra, C.-T. Lin, J. A. London, K. D. Hansen, R. Fishel, T. Ha
The paper tracks DNA mismatch repair in E. coli using high-throughput sequencing and finds sequence-dependent repair efficiencies, with CC mismatches being poorly repaired and local context affecting TT, AG, and CT mismatches.
bioRxiv · Jan 8, 2023 · PreprintBiophysics