Lineage plasticity in SCLC generates non-neuroendocrine cells primed for vasculogenic mimicry
S. M. Pearsall, S. C. Williamson, F. J. Garcia Marques, S. Humphrey, E. Hughes, Y. T. Shue, A. Bermudez, K. Frese, M. Galvin, M. Carter, L. Preist, A. Kerr, C. Zhou, T. G. Oliver, J. D. Humphries, , C. Dive
This study identifies VM-competent non-neuroendocrine cells in SCLC that support vessel formation and tumor growth through integrin β1-dependent ECM remodeling.
Journal of Thoracic Oncology · Oct 1, 2023Peer-reviewedCancer Biology