Safety and Efficacy of Avaren-Fc Lectibody Targeting HCV High-Mannose Glycans in a Human Liver Chimeric Mouse Model
M. Dent, K. Hamorsky, T. Vausselin, J. D. Dubuisson, Y. Miyata, Y. Morikawa, N. Matoba
This paper evaluates the safety and efficacy of Avaren-Fc, a HCV-targeting lectibody, in a human liver chimeric mouse model, showing it prevents HCV infection without toxicity.
bioRxiv · Apr 22, 2020Pharmacology & Toxicology