Author

J. D. Dubuisson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Assay:metabolomics· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

C. Riviere· 2 shared K. Seron· 2 shared S. Sahpaz· 2 shared A. Goffard· 1 shared A. Rosenberg· 1 shared A. Tarricone· 1 shared A. Vandeputte· 1 shared C. Camuzet· 1 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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2 shared papersMicrobiology

C. Riviere

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Major Metabolites From Hypericum perforatum L., Hyperforin And Hypericin, Are Both Active Against Human Coronaviruses

I. Raczkiewicz, C. Riviere, P. Bouquet, L. Desmarets, A. Tarricone, C. Camuzet, N. Francois, G. Lefevre, J. Samaillie, F. Silva Angulo, C. Robil, F. Trottein, S. Sahpaz, J. D. Dubuisson, S. Belouzard, , K. Seron

This study shows that hyperforin from Hypericum perforatum inhibits multiple coronaviruses, including SARS-CoV-2, with antiviral activity confirmed in human cells and potential for combination therapy with remdesivir.

bioRxiv · Apr 9, 2024 · PreprintMicrobiology

Safety and Efficacy of Avaren-Fc Lectibody Targeting HCV High-Mannose Glycans in a Human Liver Chimeric Mouse Model

M. Dent, K. Hamorsky, T. Vausselin, J. D. Dubuisson, Y. Miyata, Y. Morikawa, N. Matoba

This paper evaluates the safety and efficacy of Avaren-Fc, a HCV-targeting lectibody, in a human liver chimeric mouse model, showing it prevents HCV infection without toxicity.

bioRxiv · Apr 22, 2020Pharmacology & Toxicology

Dehydrojuncusol, a Natural Phenanthrene Compound Extracted from Juncus maritimus Is a New Inhibitor of Hepatitis C Virus Replication

M.-E. Sahuc, R. Sahli, C. Riviere, V. Pene, M. Lavie, A. Vandeputte, P. Brodin, A. Rosenberg, J. D. Dubuisson, R. Ksouri, Y. Rouille, S. Sahpaz, K. Seron

This paper identifies dehydrojuncusol, a natural compound from Juncus maritimus, as a new inhibitor of HCV replication that targets NS5A and is effective against DAA-resistant variants.

bioRxiv · Nov 14, 2018Microbiology

New insights into the ORF2 capsid protein, a key player of the hepatitis E virus lifecycle

M. Ankavay, C. Montpellier, I. M. Sayed, J.-M. Saliou, C. Wychowski, L. Saas, S. Duvet, C.-M. Aliouat-Denis, R. Farhat, V. de Masson d'Autume, P. Meuleman, J. D. Dubuisson, L. Cocquerel

This study characterizes the glycosylation of HEV ORF2 protein and its role in viral lifecycle, showing that glycosylation does not affect particle assembly but contributes to antigenicity and nuclear translocation of ORF2i.

bioRxiv · Oct 5, 2018Microbiology