Rate-limiting transport of positive charges through the Sec-machinery is integral to the mechanism of protein transport
W. J. Allen, R. A. Corey, D. W. Watkins, A. S. F. Oliveira, K. Hards, G. M. Cook, I. Collinson
The paper investigates protein transport through the Sec-machinery, finding that arginine diffusion limits transport and PMF contributes via a proton ratchet mechanism.
bioRxiv · Feb 2, 2022Biochemistry