R. Grinter

High-affinity PQQ import is widespread in Gram-negative bacteria

The paper identifies PqqU as a high-affinity PQQ importer in Gram-negative bacteria, showing its structural basis and widespread distribution across diverse environments.

Obtaining high-resolution cryo-EM structures using a common LaB6, 120-keV electron microscope equipped with a sub 200-keV optimised direct electron detector.

This paper demonstrates that a standard 120-keV TEM with a direct electron detector can achieve high-resolution cryo-EM reconstructions of various proteins.

Quinone extraction drives atmospheric carbon monoxide oxidation in bacteria

This study identifies how Mo-CODH and CoxG in Mycobacterium smegmatis oxidize CO and transfer electrons to the respiratory chain via quinone transport.

Metabolism of ʟ -arabinose converges with virulence regulation to promote enteric pathogen fitness

This study shows that arabinose metabolism in enteric pathogens enhances virulence by regulating key factors, improving fitness during infection.

An obligate aerobe adapts to hypoxia by hybridising fermentation with carbon storage

This study reveals how Mycobacterium smegmatis adapts to hypoxia by combining fermentative hydrogen production with carbon storage through lipid droplets.

Atmospheric hydrogen oxidation extends to the domain archaea

This study shows that archaea, like bacteria, oxidize atmospheric hydrogen and carbon monoxide, revealing a cross-domain metabolic trait with ecological and evolutionary significance.

Energy extraction from air: structural basis of atmospheric hydrogen oxidation

This paper determines the structure of a mycobacterial hydrogenase and explains how it selectively oxidizes atmospheric H2 while avoiding O2, enabling energy extraction from air.

Mycobacteria tolerate carbon monoxide by remodelling their respiratory chain

This study shows Mycobacterium smegmatis resists carbon monoxide by using cytochrome bd oxidase and shows minimal proteomic changes.

BonA from Acinetobacter baumannii forms a divisome-localized decamer that supports outer envelope function

This study identifies BonA as an outer membrane protein in Acinetobacter baumannii that forms a transient decamer, supports outer envelope function, and is involved in cell division and motility.

A genome compendium reveals diverse metabolic adaptations of Antarctic soil microorganisms

This study identifies diverse metabolic adaptations of Antarctic soil microorganisms using metagenomic analysis and experimental validation.

A widely distributed hydrogenase oxidises atmospheric H2 during bacterial growth

This study investigates the role of group 2a [NiFe]-hydrogenase in three bacterial species, finding it supports aerobic H2 oxidation during growth and is widely distributed across 13 bacterial phyla.

Cellular and structural basis of synthesis of the unique intermediate dehydro-F420-0 in mycobacteria

This study resolves the biosynthesis pathway of F420 in mycobacteria by showing phosphoenolpyruvate, not 2-phospholactate, is the precursor and identifies the structural mechanism of dehydro-F420-0 production.

The crystal structure of the TonB-dependent transporter YncD reveals a positively charged substrate binding site.

The paper determines the crystal structure of YncD, a TonB-dependent transporter, revealing a positively charged substrate-binding site, but shows it does not contribute to iron transport in E. coli.

Two uptake hydrogenases differentially interact with the aerobic respiratory chain during mycobacterial growth and persistence

This study identifies two hydrogenases in Mycobacterium smegmatis that differentially interact with the respiratory chain during growth and persistence, performing distinct roles under varying conditions.

The structure of the iron-catecholate transporter Fiu suggests substrate import occurs via a 2-step mechanism

The paper determines the structure of the Fiu transporter and reveals a 2-step mechanism for substrate import, which has implications for antibiotic development.

Plumage redness signals mitochondrial function in the House Finch

The paper links carotenoid oxidation and feather redness to mitochondrial function in house finches, showing a direct relationship between mitochondrial performance and feather coloration.

Engineering bacteriocin-mediated resistance against plant pathogenic bacteria in plants

This paper demonstrates that expressing the bacteriocin putidacin L1 in plants provides effective resistance against Pseudomonas syringae and related pathogens.