Structure of the triose-phosphate/phosphate translocator reveals the basis of substrate specificity
Y. Lee, T. Nishizawa, M. Takemoto, K. Kumazaki, K. Yamashita, K. Hirata, A. Minoda, S. Nagatoishi, K. Tsumoto, R. Ishitani, O. Nureki
This study determines the crystal structures of TPT bound to substrates, revealing the molecular basis of its strict 1:1 exchange mechanism.
bioRxiv · Aug 18, 2017Biochemistry