Author

K. Lage

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:statistical model· 2 Assay:whole-exome sequencing· 2 Approach:deep learning· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

H. Horn· 2 shared A. Gupta· 1 shared A. Kamburov· 1 shared A. Kashani· 1 shared C. Fagre· 1 shared C. R. Chouinard· 1 shared E. Kim· 1 shared E. Shea· 1 shared

Activity by Year

2017-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersCancer Biology

H. Horn

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2 papers

Recent·Most cited

Using protein interaction networks to identify cancer dependencies from tumor genome data

H. Horn, C. Fagre, A. Gupta, K. Tsafou, N. Fornelos, J. T. Neal, K. Lage

This paper develops an algorithm to predict cancer dependencies from tumor genomes by analyzing protein interaction networks and validates its predictions using CRISPR screens.

bioRxiv · Aug 27, 2020 · PreprintCancer Biology

Expanding discovery from cancer genomes by integrating protein network analyses with in vivo tumorigenesis assays

H. Horn, M. S. Lawrence, C. R. Chouinard, Y. Shrestha, J. Xin Hu, E. Worstell, E. Shea, N. Ilic, E. Kim, A. Kamburov, A. Kashani, J. D. Campbell, W. C. Hahn, J. S. Boehm, G. Getz, K. Lage

The paper develops a method to identify new cancer genes by integrating protein network analysis with in vivo tumorigenesis assays, finding 62 new candidates and validating two in patient data.

bioRxiv · Oct 30, 2017Cancer Biology