Genetic variation/evolution and differential host responses resulting from in-patient adaptation of Mycobacterium avium
N. Kannan, Y.-P. Lai, M. Haug, K. Lilleness, S. S. Bakke, A. Marstad, H. Hov, T. Naustdal, J. E. Afset, T. R. Ioerger, T. H. Flo, M. Steigedal
This study examines genetic changes in Mycobacterium avium isolates from infected patients over time and links these changes to altered host immune responses and increased bacterial persistence.
bioRxiv · Apr 10, 2018Immunology