Sequential action of a tRNA base editor in conversion of cytidine to pseudouridine
S. Kimura, V. Srisuknimit, K. McCarty, P. C. Dedon, P. J. Kranzusch, M. K. Waldor
The paper characterizes a sequential C-to-U and U-to-Ψ RNA editing process in Vibrio cholerae tRNA mediated by TrcP, revealing its role in coupling tRNA modification states to iron availability.
bioRxiv · Feb 17, 2022Biochemistry