Author

K. Miles

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Assay:scRNA-seq· 2 Research Focus:clustering· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:machine learning (classical)· 1 Assay:proteomics· 1

Frequent Co-Authors

C. Goodyear· 2 shared D. Gray· 2 shared G. J. M. Cowan· 2 shared M. Gray· 2 shared S. Breusch· 2 shared C. Sutherland· 1 shared E. Wing· 1 shared H. Johnsson· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersImmunology

C. Goodyear

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2 papers

Recent·Most cited

A comprehensive analysis of rheumatoid arthritis B cells reveals the importance of CD11c+ve double-negative-2 B cells as the major synovial plasma cell precursor.

E. Wing, C. Sutherland, K. Miles, D. Gray, C. Goodyear, T. D. Otto, S. Breusch, G. J. M. Cowan, M. Gray

This study identifies CD11c+ve double-negative-2 B cells as the major synovial plasma cell precursor in rheumatoid arthritis using single-cell RNA and repertoire sequencing.

bioRxiv · Feb 15, 2023 · PreprintImmunology

Rheumatoid arthritis patients express a skewed repertoire of polyclonal, hypomutated B-cell receptors

G. J. M. Cowan, K. Miles, L. Capitani, S. S. B. Giguere, H. Johnsson, C. Goodyear, I. B. McInnes, Scottish Early Rheumatoid Arthritis Inception cohort Investigators, S. Breusch, D. Gray, M. Gray

This study identifies that RA patients have a higher proportion of poorly mutated, polyclonal IgG+ve BCRs in peripheral blood and synovium, suggesting a role in autoimmune inflammation.

bioRxiv · Sep 18, 2019 · PreprintImmunology