M. Gray

The distribution of the hemlock woolly adelgid in Canada.

This paper maps the distribution of the hemlock woolly adelgid in Canada, identifying native and invasive populations and estimating spread rates in Nova Scotia.

Runaway resorption of microcracks contributes to age-related hip-fracture patients

The paper investigates microdefects in hip-fracture patients and finds they are more prevalent and negatively correlate with bone strength.

Airway succinate chemosensing induces CFTR-dependent anion secretion and mucus clearance which is impaired in cystic fibrosis.

Geographic risk assessment of Batrachochytrium salamandrivorans invasion in Costa Rica as a means of informing emergence management and mitigation

The paper assesses the geographic risk of Bsal invasion in Costa Rica using ecological niche modeling and identifies high-risk areas for targeted surveillance and mitigation.

A comprehensive analysis of rheumatoid arthritis B cells reveals the importance of CD11c+ve double-negative-2 B cells as the major synovial plasma cell precursor.

This study identifies CD11c+ve double-negative-2 B cells as the major synovial plasma cell precursor in rheumatoid arthritis using single-cell RNA and repertoire sequencing.

Inhibition of the sodium-dependent HCO3 -transporter SLC4A4, produces a cystic fibrosis-like airway disease phenotype.

This study shows that inhibiting SLC4A4, a sodium-dependent bicarbonate cotransporter, in airway epithelial cells causes a CF-like phenotype with mucus accumulation and reduced mucociliary clearance.

Decreased calmodulin recruitment triggers PMCA4 dysfunction and pancreatic injury in cystic fibrosis

This study shows that reduced CFTR expression in pancreatic ductal cells decreases calmodulin recruitment, leading to PMCA4 dysfunction, mitochondrial damage, and apoptosis, suggesting a potential therapeutic target for cystic fibrosis.

Detection of a multi-disease biomarker in Salivawith Graphene Field Effect Transistors

This paper develops a label-free biosensor using graphene field effect transistors to detect CA1 in saliva, achieving high sensitivity and clinical relevance.

Dielectrophoresis assisted rapid, selective and single cell detection of antibiotic resistant bacteria with G-FETs

This paper presents a biosensor using G-FETs and dielectrophoresis to rapidly and selectively detect antibiotic-resistant bacteria at the single-cell level.

Rheumatoid arthritis patients express a skewed repertoire of polyclonal, hypomutated B-cell receptors

This study identifies that RA patients have a higher proportion of poorly mutated, polyclonal IgG+ve BCRs in peripheral blood and synovium, suggesting a role in autoimmune inflammation.

Anti-HIV-1 B cell responses are dependent on B cell precursor frequency and antigen binding affinity

This study investigates how B cell precursor frequency and antigen binding affinity influence germinal center recruitment and clonal expansion in HIV-1 vaccine development using adoptive transfer experiments.