PD-1 and CTLA-4 exert additive control of effector regulatory T cells
J. A. Perry, Z. Lanzar, J. T. Clark, A. P. Hart, B. B. Douglas, L. Shallberg, K. O'Dea, D. A. Christian, C. A. Hunter
This study shows that PD-1 and CTLA-4 pathways additively regulate effector Treg cells by modulating their suppressive function and proliferation.
bioRxiv · Jul 22, 2022 · PreprintImmunology