J. T. Clark

This study shows that PD-1 and CTLA-4 pathways additively regulate effector Treg cells by modulating their suppressive function and proliferation.

This study identifies a Cryptosporidium secretion system that exports proteins into infected cells, triggering ER stress and contributing to pathogenesis.

The paper shows IL-33 enhances ILC-mediated resistance to Toxoplasma gondii by promoting IFN-γ production and reducing parasite replication.

This study shows that PD-L1-PD-1 interactions regulate Treg cell populations at homeostasis and during infection, limiting their numbers to enhance pathogen-specific CD4+ T cell responses.

This study shows that cDC1 in the omentum support T cell expansion and survival during Toxoplasma gondii infection, not T cell priming.