Reconstructing unobserved cellular states from paired single-cell lineage tracing and transcriptomics data
K. Ouardini, R. Lopez, M. G. Jones, S. Prillo, R. Zhang, M. I. Jordan, N. Yosef
The paper introduces TreeVAE, a probabilistic framework to reconstruct unobserved ancestral cellular states from single-cell lineage tracing and transcriptomics data, showing improved performance over benchmarks.
bioRxiv · May 28, 2021 · PreprintBioinformatics