Tuberculosis-associated IFN-I induces Siglec-1 on tunneling nanotubes and favors HIV-1 spread in macrophages
C. Verollet, M. Dupont, S. Souriant, L. Balboa, T. Phong, K. Pingris, S. Rousset, C. Cougoule, Y. Romboust, R. Poincloux, M. Ben Neji, C. Allers, D. Kaushal, M. J. Kuroda, S. Benet, , G. Lugo-Villarino
This study identifies Siglec-1 as a factor induced by TB-associated IFN-I that localizes on TNTs and promotes HIV-1 spread in macrophages.
bioRxiv · Nov 12, 2019Cell Biology