K. Raman

Metagenome-based metabolic modelling predicts unique microbial interactions in deep-sea hydrothermal plume microbiomes

The paper uses metagenome-based metabolic modeling to predict microbial interactions in deep-sea hydrothermal plume microbiomes, identifying key species and metabolic exchanges.

Novel ratio-metric features enable the identification of new driver genes across cancer types

This study introduces novel ratio-metric features and a model to identify new driver genes across cancer types, predicting potential novel candidates while addressing bias and low recall.

Robust lysosomal rewiring in Mtb infected macrophages mediated by Mtb lipids restricts the intracellular bacterial survival

The paper shows that Mtb lipids induce lysosomal rewiring in infected macrophages, enhancing host defense and restricting bacterial survival.

Uncovering novel pathways for enhancing hyaluronan synthesis in recombinant Lactococcus lactis: Genome-scale metabolic modelling and experimental validation

This study uses genome-scale metabolic modeling and experimental validation to identify strategies for enhancing hyaluronan synthesis in recombinant Lactococcus lactis, achieving a 2.8-fold increase in HA yield through an alternate nucleoside-based pathway.