Author

K. Siddle

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

E. Rasijeff· 1 shared G. Brierley· 1 shared G. V. Brierley· 1 shared H. Webber· 1 shared R. K. Semple· 1 shared R. Semple· 1 shared S. Grocott· 1 shared

Activity by Year

2017-2020 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 11 mutual co-author links

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1 shared paperBiochemistry

E. Rasijeff

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2 papers

Recent·Most cited

Anti-Insulin receptor antibodies improve hyperglycaemia in a mouse model of human insulin receptoropathy

G. V. Brierley, H. Webber, E. Rasijeff, S. Grocott, K. Siddle, R. Semple

Anti-insulin receptor antibodies improve glucose tolerance and reduce hyperinsulinemia in a mouse model of insulin receptoropathy but also downregulate receptor expression.

bioRxiv · Mar 20, 2020Biochemistry

Evaluation of anti insulin receptor antibodies as potential novel therapies for human insulin receptoropathy

G. Brierley, K. Siddle, R. K. Semple

Anti-insulin receptor monoclonal antibodies activate specific mutated human insulin receptors, suggesting potential as novel therapies for insulin receptoropathy.

bioRxiv · Nov 22, 2017Cell Biology